Cherokee Prairie Natural Area is one of the largest remaining tracts of tallgrass prairie in the Arkansas Valley. Located just north of Charleston, this tract is a high-quality prairie representative of the more extensive Cherokee Prairies that once occurred across the western portion of the Arkansas Valley. The natural area contains a diverse array of forb species (herbaceous species other than grasses) including compass plant, purple prairie clover, and Indian paintbrush. It also supports a number of plant and animal species that are now considered rare, or even endangered. Prairie Creek flows through the center of the natural area.

The natural area is located approximately 2 miles north of Charleston, at the intersection of state highways 60 and 217.

Specific types of hunting are allowed on this natural area. For details, see the Cherokee Prairie Natural Area WMA listing in the current Arkansas Hunting Guidebook. Take all necessary safety precautions when visiting the area.

• WAMN Hosts Work Day at Adopted Natural Area
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• Commission and Staff Tour of H.E. Flanagan Prairie Natural Area